Summary
Tablet farming has become incredibly popular in PoE 2's endgame, but crafting these tablets for maximum profit is what separates the casual farmer from the currency printer. This guide breaks down exactly how I made over 500 divines in a single day through farming, buying, and crafting tablets.

The Core Mechanic
Tablet drops scale with Waystone drop chance, but here's the catch: tablet drops are reduced if you're using that same tablet type to juice your map. Running a Breach tablet means you'll drop fewer Breach tablets.
The solution? Run Irradiated Tablets. These add random league mechanics to your map without reducing drop chances for any tablet type. You're at the mercy of RNG — sometimes you'll roll double Temple mechanics, which is less ideal — but every tablet type has lucrative crafts, so farming all of them remains extremely profitable.
Farming Tablets
For your Waystones, aim for at least 90% increased Waystone drop chance. Roll them with six mods and corrupt them — you'll frequently hit up to 130%. You don't need to buy these off trade; they're easy to roll yourself.
Run these maps on Mountain biomes if possible to get the 50% increased tablet quantity from the Mountain mastery node. Clear all league mechanics completely. Each drops its respective tablet type: Breach tablets drop at encounter end, Abyss from spawned monsters, Temple from the chest at circle encounters, Delirium from mobs throughout the map, and Ritual from ritual monsters.
In about 30 City and Mountain maps, I dropped 20 Delirium tablets, 12 Temple, 31 Breach, 26 Abyss, and 15 Ritual tablets — roughly three per map. I also made about 35 divines in other currency from splinters, emotions, and miscellaneous drops. The uncrafted tablets alone added up to 352 chaos (about 35 divines), bringing the total from those 30 maps to roughly 70 divines.
Crafting Tablets
The real money comes from crafting. Here's the process:
Start by using a Transmutation Orb and Augmentation Orb to make white tablets magic with two mods. Check for valuable modifiers. If you hit something good, use a Regal Orb and Exalted Orb to fill it out.
If you got bad modifiers, use an Alchemy Orb. This rerolls the two modifiers into four brand new ones, essentially letting you craft the tablet all over again. For truly worthless tablets, use the 3-to-1 reforging bench, then identify and slam with an Exalted Orb.
High-Value Mods by Tablet Type
Temple Tablets: Look for "unique monsters have an additional rare modifier." With increased unique monsters, this hits 45+ divines. Alone, it's still 5 divines minimum. Also watch for increased crystals gained (1-3 divines) and map has two additional modifiers (1 divine, more with juicing mods).
Delirium Tablets: No single jackpot mod — value comes from combinations. Fracturing mirrors alone is nothing. Simulacrum splinters alone is nothing. But combined with each other and generic juicing mods like rarity or effectiveness? That's 7+ divines. This was the most consistent tablet to craft, yielding 48 divines profit from 144 tablets.
Breach Tablets: The money maker is "unstable breaches spawn 1-3 additional rare monsters when stabilized." On its own, this is multiple divines. With rarity, effectiveness, or additional map modifiers, it can reach 10-30 divines. Otherwise, high hive blood dropped sells for around 100 exalts.
Ritual Tablets: The current king. "Rituals have additional rerolls" goes for ~17 divines. Combined with increased omen chance, increased tribute gained, or reduced tribute used, that value doubles or triples. From 144 tablets, I made almost 200 divines profit — over 1 divine per tablet on average. Note that ritual tablets value comes from ritual-specific modifiers, not generic juicing.
Abyss Tablets: Trickiest to price check. Look for combinations of: four additional pits, increased chance for abyssal modifiers, increased effectiveness per closed pit, additional rare monsters, monster rarity, additional map mods, item rarity, and monster effectiveness. Two of these mods warrants a price check. Three or more is almost always valuable.